Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GSR | P00390 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11253338 | 0.91 | ALDH1A1 (0.76) | ALDH1A1TSHRMEN1KMT2AGAA | |
| SCHEMBL7734714 | 0.91 | ALDH1A1 (0.81) | ALDH1A1TSHRMEN1KMT2AGAA | |
| SCHEMBL9049818 | 0.89 | KMT2A (0.59) | ALDH1A1TSHRMEN1KMT2AGAA | |
| SCHEMBL10487940 | 0.89 | ALDH1A1 (0.62) | ALDH1A1TSHRMEN1KMT2ATP53 | |
| SCHEMBL11266458 | 0.89 | ALDH1A1 (0.57) | ALDH1A1TSHRMEN1KMT2AGAA | |
| SCHEMBL11262526 | 0.88 | LMNA (0.73) | ALDH1A1TSHRMEN1KMT2AGAA | |
| SCHEMBL11263773 | 0.88 | MEN1 (0.72) | ALDH1A1TSHRMEN1KMT2AGAA | |
| SCHEMBL11266396 | 0.84 | LMNA (0.74) | ALDH1A1TSHRMEN1KMT2AGAA | |
| SCHEMBL11260065 | 0.84 | ALDH1A1 (0.69) | ALDH1A1TSHRMEN1KMT2AGAA | |
| SCHEMBL11263917 | 0.84 | ALDH1A1 (0.64) | ALDH1A1TSHRMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0019440-B1 | BENZIMIDAZOLONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PFIZER INC. (US) | 1982-09-29 | — | — | EP | disclosed |
| EP-0019440-A1 | Benzimidazolone derivatives, process for their preparation and pharmaceutical compositions containing them | PFIZER INC. (US) | 1980-11-26 | — | — | EP | disclosed |
| US-4209527-A | ANTIDIABETIC AGENTS | PFIZER INC. (US) | 1980-06-24 | — | — | US | disclosed |