Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | SI | P14410 | 4/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7224521 | 0.91 | NPC1 (0.40) | RAB9ANPC1MAPTALDH1A1KDM4E | |
| SCHEMBL7223992 | 0.86 | RAB9A (0.42) | RAB9ANPC1MAPTALDH1A1KDM4E | |
| SCHEMBL7223990 | 0.86 | RAB9A (0.42) | RAB9ANPC1MAPTALDH1A1KDM4E | |
| SCHEMBL7234111 | 0.85 | NPC1 (0.37) | RAB9ANPC1MAPTALDH1A1KDM4E | |
| SCHEMBL7225111 | 0.83 | MGAM (0.45) | RAB9ANPC1MAPTALDH1A1KDM4E | |
| SCHEMBL7232692 | 0.83 | NPC1 (0.42) | RAB9ANPC1MAPTALDH1A1KDM4E | |
| SCHEMBL7223707 | 0.83 | NPC1 (0.38) | RAB9ANPC1MAPTALDH1A1KDM4E | |
| SCHEMBL7224791 | 0.83 | NPC1 (0.44) | RAB9ANPC1MAPTALDH1A1KDM4E | |
| SCHEMBL7230164 | 0.82 | RAB9A (0.41) | RAB9ANPC1MAPTALDH1A1KDM4E | |
| SCHEMBL7234270 | 0.82 | NPC1 (0.40) | RAB9ANPC1MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |