SCHEMBL7225542

SCHEMBL7225542

NC1=CC=C2C(=Cc3cccc(N)c32)C1=O

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 3/20 0.38
PTPRC P08575 1/20 0.38
THRB P10828 1/20 0.34
FGR P09769 1/20 0.33
PIM1 P11309 1/20 0.33
MAOA P21397 1/20 0.33
CSNK1A1 P48729 1/20 0.33
CSNK1D P48730 1/20 0.33
DYRK1A Q13627 1/20 0.33
HIPK2 Q9H2X6 1/20 0.33
CSNK1G1 Q9HCP0 1/20 0.33
HSPA1A P0DMV8 1/20 0.30
PABPC1 P11940 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1882102 0.75 NSD2 (0.41) ADORA2APTPRCTHRBFGRPIM1
SCHEMBL9019022 0.66 NPC1 (0.39) PTPRC
SCHEMBL6653492 0.63 PTPN1 (0.33)
SCHEMBL5866516 0.60 ADORA2A (0.71) ADORA2APTPRCTHRBFGRPIM1
SCHEMBL21840830 0.60 ADORA2A (0.78) ADORA2APTPRCTHRBFGRPIM1
SCHEMBL29944895 0.60 ADORA2A (0.86) ADORA2APTPRCTHRBFGRPIM1
SCHEMBL64318 0.60 ADORA2A (0.86) ADORA2APTPRCTHRBFGRPIM1
SCHEMBL30594726 0.59 ADORA2A (0.57) ADORA2APTPRCTHRBFGRPIM1
SCHEMBL28371089 0.59 ADORA2A (0.57) ADORA2APTPRCTHRBFGRPIM1
SCHEMBL18347812 0.59 ADORA2A (0.57) ADORA2APTPRCTHRBFGRPIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6627377-B1 Soluble in organic solvents, which excels in adhesiveness, heat resistance, mechanical properties and flexibility, which shows properties of alkali-soluble highly sensitive positive-type photoresist PI R&D CO., LTD. (JP) 2003-09-30 US disclosed
EP-1024407-A1 POSITIVE PHOTOSENSITIVE POLYIMIDE COMPOSITION PI R & D Co Ltd (JP) 2000-08-02 EP disclosed