Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7219447 | 0.90 | SMN1; SMN2 (0.56) | KMT2AMEN1MAPTALDH1A1RXFP1 | |
| SCHEMBL6475604 | 0.88 | HDAC1 (0.49) | KMT2AMEN1MAPTALDH1A1ALOX15 | |
| Hydrochloric Acid SCHEMBL6480850 | 0.84 | MEN1 (0.53) | KMT2AMEN1MAPTALDH1A1ALOX15 | |
| SCHEMBL6474125 | 0.80 | PTGDR2 (0.64) | KMT2AMEN1ALDH1A1KDM4EPTGDR2 | |
| SCHEMBL6531341 | 0.79 | SMN1; SMN2 (0.52) | KMT2AMEN1MAPTALDH1A1RXFP1 | |
| SCHEMBL7227263 | 0.77 | PKM (0.49) | KMT2AALDH1A1TP53KDM4EPTGDR2 | |
| SCHEMBL6481086 | 0.77 | KDM4E (0.47) | KMT2AMEN1MAPTALDH1A1RXFP1 | |
| SCHEMBL6474612 | 0.76 | PTGDR2 (0.54) | KMT2AMEN1ALDH1A1KDM4EPTGDR2 | |
| SCHEMBL6480591 | 0.76 | KDM4E (0.55) | KMT2AMEN1ALDH1A1KDM4EPTGDR2 | |
| SCHEMBL6474609 | 0.75 | KDM4E (0.54) | KMT2AMEN1ALDH1A1KDM4EPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583135-B2 | Treating central nervous system disorders wherein modulation of the activity of serotonin receptors (5-HT) is desired (e.g. anxiety, depression and obesity). | PHARMACIA & UPJOHN COMPANY | 2003-06-24 | — | — | US | disclosed |