Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.63 |
| ▸ | HTT | P42858 | 5/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | CNR2 | P34972 | 1/20 | 0.60 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.55 |
| ▸ | HTR3A | P46098 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30934954 | 1.00 | MEN1 (0.70) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL30050434 | 0.86 | MEN1 (0.73) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL28595389 | 0.86 | MEN1 (0.73) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL16210700 | 0.85 | MEN1 (0.72) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL29414257 | 0.85 | MEN1 (0.72) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL29201531 | 0.84 | MEN1 (0.71) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL29201530 | 0.84 | KMT2A (0.71) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL24138327 | 0.84 | PDE5A (0.54) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL31138328 | 0.84 | PDE5A (0.54) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL4042951 | 0.84 | PDE5A (0.54) | MEN1KMT2AKDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118345387-A | Method for synthesizing silicon-based substituted quinoxalinone compound by electrochemical Minisci reaction | 江苏食品药品职业技术学院 | 2024-07-16 | — | — | CN | disclosed |
| CN-105001169-A | Synthetic method for 3-aminoquinoxaline-2(1H)-ketone compound | UNIV HUAQIAO | 2015-10-28 | — | — | CN | disclosed |
| US-6635626-B1 | T-cell mediated disorders | BRISTOL-MYERS SQUIBB CO. | 2003-10-21 | — | — | US | disclosed |
| US-6239133-B1 | IMMUNOLOGIC DISORDERS. | BRISTOL-MYERS SQUIBB COMPANY | 2001-05-29 | — | — | US | disclosed |
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | disclosed |
| WO-1999009845-A1 | IMIDAZOQUINOXALINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-04 | — | — | WO | disclosed |