SCHEMBL30050434

SCHEMBL30050434

Cc1ccc(Cn2c(=O)cnc3ccccc32)cc1

nearest known ligand 0.74

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.73
KMT2A Q03164 3/20 0.73
KDM4E B2RXH2 7/20 0.65
ALDH1A1 P00352 6/20 0.65
LMNA P02545 5/20 0.65
HSD17B10 Q99714 3/20 0.65
TSHR P16473 1/20 0.65
HTT P42858 4/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
CYP11B1 P15538 1/20 0.56
CYP11B2 P19099 1/20 0.56
TDP1 Q9NUW8 2/20 0.56
TP53 P04637 2/20 0.56
HPGD P15428 1/20 0.55
P2RX4 Q99571 1/20 0.54
MAPT P10636 1/20 0.53
NPSR1 Q6W5P4 2/20 0.53
BRD4 O60885 1/20 0.52
HTR3A P46098 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28595389 1.00 MEN1 (0.73) MEN1KMT2AKDM4EALDH1A1LMNA
SCHEMBL16210700 0.88 MEN1 (0.72) MEN1KMT2AKDM4EALDH1A1LMNA
SCHEMBL29414257 0.88 MEN1 (0.72) MEN1KMT2AKDM4EALDH1A1LMNA
SCHEMBL29201531 0.87 MEN1 (0.71) MEN1KMT2AKDM4EALDH1A1LMNA
SCHEMBL29201530 0.87 KMT2A (0.71) MEN1KMT2AKDM4EALDH1A1LMNA
SCHEMBL7225918 0.86 MEN1 (0.70) MEN1KMT2AKDM4EALDH1A1LMNA
SCHEMBL30934954 0.86 MEN1 (0.70) MEN1KMT2AKDM4EALDH1A1LMNA
SCHEMBL29201529 0.85 MEN1 (0.69) MEN1KMT2AKDM4EALDH1A1LMNA
SCHEMBL29201528 0.85 MEN1 (0.69) MEN1KMT2AKDM4EALDH1A1LMNA
SCHEMBL28898445 0.85 KMT2A (0.61) MEN1KMT2AKDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119684221-A Synthesis method and application of C-3-hydroxyfluoroalkyl substituted quinoxalinone derivative 天津科技大学 2025-03-25 CN claimed
CN-119684221-A Synthesis method and application of C-3-hydroxyfluoroalkyl substituted quinoxalinone derivative 天津科技大学 2025-03-25 CN disclosed
CN-112961112-B (Z) -enaminone compound and synthesis method thereof 杭州师范大学 2022-12-13 CN disclosed