Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | HBB | P68871 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | BRD4 | O60885 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CFTR | P13569 | 1/20 | 0.54 |
| ▸ | TNF | P01375 | 2/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29414257 | 1.00 | MEN1 (0.72) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL29201531 | 0.89 | MEN1 (0.71) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL29201530 | 0.89 | KMT2A (0.71) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL30050434 | 0.88 | MEN1 (0.73) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL28595389 | 0.88 | MEN1 (0.73) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL29201528 | 0.88 | MEN1 (0.69) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL29201529 | 0.88 | MEN1 (0.69) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL17585774 | 0.87 | CYP11B1 (0.59) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL29489100 | 0.85 | ALDH1A1 (0.63) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL28357168 | 0.85 | ALDH1A1 (0.63) | MEN1KMT2AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111689951-A | Synthesis method of 1-benzyl-3-alkyl quinoxaline-2 (1H) -ketone | 西北师范大学 | 2020-09-22 | — | — | CN | claimed |
| CN-120025287-A | Method for catalyzing coupling reaction of quinoxalinone and derivative thereof and electrophile by using lithium silicon amide | 苏州大学 | 2025-05-23 | — | — | CN | disclosed |
| CN-119663301-A | Preparation method and application of C3-cyanoalkyl substituted quinoxalinone | 安阳工学院 | 2025-03-21 | — | — | CN | disclosed |
| CN-118345387-A | Method for synthesizing silicon-based substituted quinoxalinone compound by electrochemical Minisci reaction | 江苏食品药品职业技术学院 | 2024-07-16 | — | — | CN | disclosed |
| CN-118345388-A | Method for preparing pyrazolone substituted quinoxalinone derivative through electrochemical promotion | 桂林理工大学 | 2024-07-16 | — | — | CN | disclosed |
| CN-114524773-B | Synthesis method of aryl quinoxaline compound promoted by mechanical force | 浙江工业大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-118047727-A | Method for preparing quinoxaline-2, 3-diketone compound by virtue of regioselective photocatalytic oxidation | 浙江工业大学台州研究院 | 2024-05-17 | — | — | CN | disclosed |
| CN-117756849-A | Preparation method of alkyl thiophosphate compounds containing quinoxalinone structural units | 湖南科技学院 | 2024-03-26 | — | — | CN | disclosed |
| CN-113861121-B | Novel method for generating 2, 3-dihydroxyquinoxaline and derivatives thereof through direct oxidation | 桂林理工大学 | 2023-11-17 | — | — | CN | disclosed |
| CN-116789610-A | Photocatalytic preparation method of quinoxaline-2, 3-diketone compound | 湖南科技学院 | 2023-09-22 | — | — | CN | disclosed |
| CN-107235923-B | Preparation method of 3-aryl quinoxalinone derivatives | 河南工业大学 | 2020-01-21 | — | — | CN | disclosed |
| CN-110627734-A | Preparation method of 3-alkoxy substituted quinoxalinone derivative | 浙江工业大学 | 2019-12-31 | — | — | CN | disclosed |
| US-9527834-B2 | Substituted 1-benzylquinoxalin-2(1H)-one analogs as positive allosteric modulators of muscarinic acetylcholine receptor M1 | VANDERBILT UNIVERSITY (US) | 2016-12-27 | — | — | US | disclosed |
| US-9527834-B2 | Substituted 1-benzylquinoxalin-2(1H)-one analogs as positive allosteric modulators of muscarinic acetylcholine receptor M1 | VANDERBILT UNIVERSITY (US) | 2016-12-27 | — | — | US | disclosed |
| US-9527834-B2 | Substituted 1-benzylquinoxalin-2(1H)-one analogs as positive allosteric modulators of muscarinic acetylcholine receptor M1 | VANDERBILT UNIVERSITY (US) | 2016-12-27 | — | — | US | disclosed |
| US-20160075690-A1 | SUBSTITUTED 1-BENZYLQUINOXALIN-2(1H) ANALOGS AS POSITIVE ALLOSTERIC MODULATORS OF MUSCARINIC ACETYLCHOLINE RECEPTOR M1 | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-03-17 | — | — | US | disclosed |
| US-20160075690-A1 | SUBSTITUTED 1-BENZYLQUINOXALIN-2(1H) ANALOGS AS POSITIVE ALLOSTERIC MODULATORS OF MUSCARINIC ACETYLCHOLINE RECEPTOR M1 | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-03-17 | — | — | US | disclosed |
| CN-105001169-A | Synthetic method for 3-aminoquinoxaline-2(1H)-ketone compound | UNIV HUAQIAO | 2015-10-28 | — | — | CN | disclosed |
| WO-2014179226-A1 | SUBSTITUTED 1-BENZYLQUINOXALIN-2 (1H)-ONE ANALOGS AS POSITIVE ALLOSTERIC MODULATORS OF MUSCARINIC ACETYLCHOLINE RECEPTOR M1 | VANDERBILT UNIVERSITY (US) | 2014-11-06 | — | — | WO | disclosed |
| WO-2014179226-A1 | SUBSTITUTED 1-BENZYLQUINOXALIN-2 (1H)-ONE ANALOGS AS POSITIVE ALLOSTERIC MODULATORS OF MUSCARINIC ACETYLCHOLINE RECEPTOR M1 | VANDERBILT UNIVERSITY (US) | 2014-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160075690-A1 | SUBSTITUTED 1-BENZYLQUINOXALIN-2(1H) ANALOGS AS POSITIVE ALLOSTERIC MODULATORS OF MUSCARINIC ACETYLCHOLINE RECEPTOR M1 | CHRM1, CHRM2, CHRM5 | MEN1 1762/4885KMT2A 837/4885ALDH1A1 2705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.