Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7235144 | 0.83 | PARP14 (0.69) | LMNAALDH1A1GAAPARP14L3MBTL1 | |
| SCHEMBL8157925 | 0.80 | KMT2A (0.60) | KMT2AMEN1LMNACYP2D6ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6621117 | 0.80 | KMT2A (0.58) | KMT2AMEN1LMNACYP2D6ALDH1A1 | |
| Fumaric Acid SCHEMBL7227141 | 0.79 | PARP14 (0.65) | KMT2AMEN1LMNAHTTPARP14 | |
| Fumaric Acid SCHEMBL7227144 | 0.79 | PARP14 (0.65) | KMT2AMEN1LMNAHTTPARP14 | |
| Fumaric Acid SCHEMBL7226160 | 0.78 | PARP14 (0.56) | LMNAALDH1A1GAAPARP14KCNH2 | |
| Fumaric Acid SCHEMBL7226163 | 0.78 | PARP14 (0.56) | LMNAALDH1A1GAAPARP14KCNH2 | |
| SCHEMBL11133461 | 0.71 | KMT2A (0.72) | KMT2AMEN1LMNACYP2D6ALDH1A1 | |
| SCHEMBL7227730 | 0.70 | PARP14 (0.46) | KMT2AMEN1TSHRPARP14 | |
| SCHEMBL15275436 | 0.70 | KMT2A (0.83) | KMT2AMEN1LMNACYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610694-B1 | Suppressing histamine and/or eosinophil chemotaxis; treating allergic diseases | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-08-26 | — | — | US | disclosed |
| EP-1120418-A1 | FUSED PYRIDAZINE COMPOUNDS, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2001-08-01 | — | — | EP | disclosed |