Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 2/20 | 0.69 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL7226163 | 0.89 | PARP14 (0.56) | PARP14ALOX5P2RX7ALDH1A1L3MBTL1 | |
| Fumaric Acid SCHEMBL7226160 | 0.89 | PARP14 (0.56) | PARP14ALOX5P2RX7ALDH1A1L3MBTL1 | |
| SCHEMBL7226445 | 0.83 | KMT2A (0.58) | PARP14ALDH1A1L3MBTL1LMNAGAA | |
| SCHEMBL6619343 | 0.81 | ALDH1A1 (0.52) | PARP14ALOX5P2RX7ALDH1A1L3MBTL1 | |
| SCHEMBL7227730 | 0.80 | PARP14 (0.46) | PARP14P2RX7 | |
| Hydrochloric Acid SCHEMBL7004707 | 0.79 | ALOX5 (0.53) | PARP14ALOX5P2RX7ALDH1A1L3MBTL1 | |
| SCHEMBL7234890 | 0.78 | PARP14 (0.68) | PARP14P2RX7MAPK1 | |
| SCHEMBL6633296 | 0.78 | PARP14 (0.93) | PARP14LMNAMAPK1 | |
| SCHEMBL7233408 | 0.76 | PARP14 (0.91) | PARP14LMNAMAPK1 | |
| Fumaric Acid SCHEMBL7225810 | 0.76 | PARP14 (0.86) | PARP14LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610694-B1 | Suppressing histamine and/or eosinophil chemotaxis; treating allergic diseases | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-08-26 | — | — | US | disclosed |
| EP-1120418-A1 | FUSED PYRIDAZINE COMPOUNDS, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2001-08-01 | — | — | EP | disclosed |