Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | BID | P55957 | 3/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL634123 | 0.95 | GRIN2D (0.40) | GRIN2DGRIN2AGRIN2BGRIN2CHDAC3 | |
| SCHEMBL722646 | 0.94 | GRIN2D (0.40) | GRIN2DGRIN2AGRIN2BGRIN2CHDAC3 | |
| SCHEMBL541844 | 0.92 | HDAC3 (0.36) | GRIN2DGRIN2AGRIN2BGRIN2CHDAC3 | |
| SCHEMBL541811 | 0.91 | RARB (0.37) | GRIN2DGRIN2AGRIN2BGRIN2CRARB | |
| SCHEMBL721324 | 0.90 | METAP2 (0.40) | GRIN2DGRIN2AGRIN2BGRIN2CRARB | |
| SCHEMBL16295022 | 0.90 | PPARA (0.45) | RARBBIDMCL1BCL2L1BAK1 | |
| SCHEMBL721325 | 0.90 | METAP2 (0.40) | GRIN2DGRIN2AGRIN2BGRIN2CRARB | |
| SCHEMBL721825 | 0.90 | BID (0.38) | GRIN2DGRIN2AGRIN2BGRIN2CRARB | |
| SCHEMBL10818422 | 0.90 | BID (0.38) | GRIN2DGRIN2AGRIN2BGRIN2CRARB | |
| SCHEMBL23670 | 0.90 | BID (0.38) | GRIN2DGRIN2AGRIN2BGRIN2CRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8648001-B2 | Aminosilane compounds, catalyst components and catalysts for olefin polymerization, and process for production of olefin polymers with the same | TOHO TITANIUM CO., LTD. (JP) | 2014-02-11 | — | — | US | disclosed |
| US-20120053310-A1 | Aminosilane Compounds, Catalyst Components and Catalysts for Olefin Polymerization, and Process for Production of Olefin Polymers with the Same | TOHO TITANIUM CO., LTD. (JP) | 2012-03-01 | — | — | US | disclosed |