Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 10/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7225724 | 0.85 | MAPT (0.51) | KDM4EL3MBTL1MAPTALDH1A1GAA | |
| SCHEMBL7225728 | 0.84 | MAPT (0.50) | KDM4EL3MBTL1MAPTALDH1A1GAA | |
| SCHEMBL7234000 | 0.84 | MAPT (0.50) | KDM4EL3MBTL1MAPTALDH1A1GAA | |
| SCHEMBL14918993 | 0.80 | KDM4E (0.71) | KDM4EL3MBTL1MAPTALDH1A1CYP1A2 | |
| SCHEMBL7225742 | 0.79 | KDM4E (1.00) | KDM4EL3MBTL1MAPTALDH1A1RAB9A | |
| SCHEMBL7227892 | 0.75 | ALDH1A1 (0.52) | KDM4EMAPTALDH1A1GAAPOLB | |
| SCHEMBL16173477 | 0.75 | KDM4E (0.73) | KDM4EL3MBTL1MAPTALDH1A1GAA | |
| SCHEMBL69458 | 0.75 | MAPT (0.75) | KDM4EMAPTALDH1A1GAACYP1A2 | |
| SCHEMBL11908685 | 0.73 | POLB (0.47) | KDM4EL3MBTL1MAPTALDH1A1GAA | |
| SCHEMBL7233982 | 0.72 | KMT2A (0.55) | KDM4EL3MBTL1MAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610853-B1 | N-(phenylsulfonyl)picolinamide derivatives, process for producing the same, and herbicide | KUREHA KAGAKU KOGYO K.K. (JP) | 2003-08-26 | — | — | US | disclosed |
| EP-1069112-A1 | N-(PHENYLSULFONYL) PICOLINAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND HERBICIDE | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-01-17 | — | — | EP | disclosed |