Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1145732 | 0.91 | — | — | |
| SCHEMBL17020105 | 0.83 | PDK1 (0.33) | — | |
| SCHEMBL21430659 | 0.83 | — | — | |
| SCHEMBL22454266 | 0.83 | PDE1B (0.34) | PDE1BPDE1C | |
| SCHEMBL12015522 | 0.83 | — | — | |
| SCHEMBL5244 | 0.78 | — | — | |
| SCHEMBL87257 | 0.78 | — | — | |
| SCHEMBL24385596 | 0.77 | LMNA (0.31) | — | |
| SCHEMBL15491974 | 0.77 | — | — | |
| SCHEMBL1145946 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6624173-B1 | Characterized by an alteration in normal neurotransmitter release, such as dopamine release (e.g., Parkinsonism, Parkinson's Disease, Tourette's Syndrome, attention deficient disorder, or schizophrenia) treated by | TARGACEPT, INC. | 2003-09-23 | — | — | US | disclosed |