Carbamic Acid

Carbamic Acid

SCHEMBL722691

N.NC(=O)O.NC(=O)O.NC(=O)O

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.88
LMNA P02545 5/20 0.56
ALDH1A1 P00352 4/20 0.56
TDP1 Q9NUW8 4/20 0.56
OR51E2 Q9H255 2/20 0.56
LDHA P00338 3/20 0.55
LDHB P07195 1/20 0.55
BLM P54132 5/20 0.46
PMP22 Q01453 4/20 0.46
ALOX15 P16050 2/20 0.46
CA2 P00918 2/20 0.44
CA9 Q16790 2/20 0.44
CA1 P00915 1/20 0.44
CYP3A4 P08684 4/20 0.39
TSHR P16473 4/20 0.39
HSD17B10 Q99714 3/20 0.39
NFKB1 P19838 2/20 0.39
HPGD P15428 2/20 0.39
CYP1A2 P05177 2/20 0.39
THPO P40225 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbamic Acid SCHEMBL453944 1.00
Carbamic Acid SCHEMBL304822 1.00
Carbamic Acid SCHEMBL7077008 1.00 ACHE (0.88) ACHELMNAALDH1A1TDP1OR51E2
Carbamic Acid SCHEMBL49149 1.00
Carbamic Acid SCHEMBL11773571 1.00 ACHE (0.88) ACHELMNAALDH1A1TDP1OR51E2
Carbamic Acid SCHEMBL27778731 1.00
Carbamic Acid SCHEMBL28049031 1.00 ACHE (0.88) ACHELMNAALDH1A1TDP1OR51E2
Carbamic Acid SCHEMBL7077007 1.00 ACHE (0.88) ACHELMNAALDH1A1TDP1OR51E2
Carbamic Acid SCHEMBL3862844 0.94
Carbamic Acid SCHEMBL9118128 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117466815-A Synthesis method of azaanthrone compound 西北工业大学 2024-01-30 CN claimed
CN-117466815-A Synthesis method of azaanthrone compound 西北工业大学 2024-01-30 CN disclosed
US-20220298161-A1 PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF SPIROGEN SARL (CH) 2022-09-22 US disclosed
US-11135303-B2 Pyrrolobenzodiazepines and conjugates thereof MEDIMMUNE LIMITED (GB) 2021-10-05 US disclosed
CN-112772393-A Method for amphibious fallow in farmland 上海开太鱼文化发展有限公司 2021-05-11 CN disclosed
EP-2970340-B1 BETA-LACTAMASE INHIBITORS VENATORX PHARMACEUTICALS INC (US) 2020-02-12 EP disclosed
US-10294248-B2 Beta-lactamase inhibitors VenatoRx Pharmaceuticals, Inc. (US) 2019-05-21 US disclosed
CN-106164191-B Paint resin combination, formed body, image display device 捷恩智株式会社 2019-04-12 CN disclosed
US-20180273552-A1 BETA-LACTAMASE INHIBITORS NATIONAL INSTITUTES OF HEALTH 2018-09-27 US disclosed
US-20180134717-A1 PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF SPIROGEN LIMITED (GB) 2018-05-17 US disclosed
US-20120053342-A1 METHOD FOR MAKING CARBAMATES, UREAS AND ISOCYANATES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-03-01 US disclosed
US-8058469-B2 Method for making carbamates, ureas and isocyanates SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-11-15 US disclosed
WO-2011130598-A1 PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF SPIROGEN LIMITED (GB) 2011-10-20 WO disclosed
US-20110256157-A1 PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF SPIROGEN LIMITED (GB) 2011-10-20 US disclosed
EP-2362867-A2 METHOD FOR MAKING CARBAMATES, UREAS AND ISOCYANATES SABIC Innovative Plastics IP B.V. (NL) 2011-09-07 EP disclosed
CN-1270889-C Buffer derive including improved flexible partition film NIKE INTERNAT CO LTD (US) 2006-08-23 CN disclosed
CN-1054261-C Plant treatment agents BAYER AGROCHEM KK (JP) 2000-07-12 CN disclosed
CN-1046723-C Tetracyclic compounds as dopamine agonists ABBOTT LAB (US) 1999-11-24 CN disclosed
CN-1124489-A Tetracyclic compounds as dopamine agonists ABBOTT LAB (US) 1996-06-12 CN disclosed
CN-1078850-A The method of control harmful insect BAYER AGROCHEM KK (JP) 1993-12-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180273552-A1 BETA-LACTAMASE INHIBITORS MGAM, GAA, LCT ACHE 13/4885LMNA 542/4885ALDH1A1 305/4885
US-10294248-B2 Beta-lactamase inhibitors MGAM, GAA, LCT ACHE 13/4885LMNA 542/4885ALDH1A1 305/4885
US-20110256157-A1 PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF HDAC10, PBDC1, PDCD10 ACHE 4855/4885LMNA 2456/4885ALDH1A1 1192/4885
US-20180134717-A1 PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF HDAC10, PBDC1, PDCD10 ACHE 4855/4885LMNA 2456/4885ALDH1A1 1192/4885
US-11135303-B2 Pyrrolobenzodiazepines and conjugates thereof CD79B, BCL6B, DRD1 ACHE 3134/4885LMNA 3435/4885ALDH1A1 1055/4885
US-20220298161-A1 PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF HDAC10, PBDC1, PDCD10 ACHE 4855/4885LMNA 2456/4885ALDH1A1 1192/4885
US-20120053342-A1 METHOD FOR MAKING CARBAMATES, UREAS AND ISOCYANATES CPS1, ALKBH3, IDH3A ACHE 35/4885LMNA 2106/4885ALDH1A1 2343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.