SCHEMBL722724

SCHEMBL722724

CNC([SiH3])(NC)C1CCCCC1

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
CA12 O43570 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24761927 0.72 SSTR4 (0.41) EPHX1SIGMAR1
SCHEMBL26353635 0.72 SSTR4 (0.41) EPHX1SIGMAR1
SCHEMBL14639632 0.72 SSTR4 (0.41) EPHX1SIGMAR1
SCHEMBL15915221 0.70 ALDH1A1 (0.32)
SCHEMBL3887312 0.69 MEN1 (0.33) EPHX1
SCHEMBL12520913 0.68 SIGMAR1 (0.31) SIGMAR1
Dimethylamine SCHEMBL28285682 0.67 EPHX1 (0.42) EPHX1SIGMAR1CA12CA7CA9
Dimethylamine SCHEMBL28284740 0.67 EPHX1 (0.42) EPHX1SIGMAR1CA12CA7CA9
SCHEMBL15915718 0.66 ALDH1A1 (0.33)
SCHEMBL15915006 0.65 MEN1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8648001-B2 Aminosilane compounds, catalyst components and catalysts for olefin polymerization, and process for production of olefin polymers with the same TOHO TITANIUM CO., LTD. (JP) 2014-02-11 US disclosed
US-20120053310-A1 Aminosilane Compounds, Catalyst Components and Catalysts for Olefin Polymerization, and Process for Production of Olefin Polymers with the Same TOHO TITANIUM CO., LTD. (JP) 2012-03-01 US disclosed
US-20100190942-A1 AMINOSILANE COMPOUNDS, CATALYST COMPONENTS AND CATALYSTS FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS WITH THE SAME TOHO CATALYST CO., LTD. (JP) 2010-07-29 US disclosed
EP-1908767-A1 AMINOSILANE COMPOUNDS, CATALYST COMPONENTS AND CATALYSTS FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS WITH THE SAME Toho Catalyst Co., Ltd. (JP) 2008-04-09 EP disclosed