Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
| ▸ | ADH7 | P40394 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25396741 | 0.76 | CYP1A2 (0.38) | SIGMAR1CYP1A2ADH1BADH1CADH1A | |
| SCHEMBL21799276 | 0.73 | CYP1A2 (0.34) | CYP1A2CHRM5ADRA2C | |
| SCHEMBL3005945 | 0.73 | SIGMAR1 (0.34) | SIGMAR1CYP1A2 | |
| SCHEMBL29030426 | 0.70 | CYP1A2 (0.40) | SIGMAR1CYP1A2ADH1BADH1CADH1A | |
| Decarboxylated Derivative SCHEMBL17975812 | 0.69 | CYP2D6 (0.52) | SIGMAR1CYP1A2ADH1BADH1CADH1A | |
| Dimethylamine SCHEMBL152274 | 0.67 | SIGMAR1 (0.44) | SIGMAR1CYP1A2ADH1BADH1CADH1A | |
| SCHEMBL28585886 | 0.67 | CYP1A2 (0.42) | SIGMAR1CYP1A2ADH1BADH1CADH1A | |
| SCHEMBL8029277 | 0.67 | CYP1A2 (0.37) | SIGMAR1CYP1A2ADH1BADH1CADH1A | |
| SCHEMBL20746876 | 0.65 | SIGMAR1 (0.54) | SIGMAR1CYP1A2ADH1BADH1CADH1A | |
| SCHEMBL21106601 | 0.65 | SIGMAR1 (0.54) | SIGMAR1CYP1A2ADH1BADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8648001-B2 | Aminosilane compounds, catalyst components and catalysts for olefin polymerization, and process for production of olefin polymers with the same | TOHO TITANIUM CO., LTD. (JP) | 2014-02-11 | — | — | US | disclosed |
| US-20120053310-A1 | Aminosilane Compounds, Catalyst Components and Catalysts for Olefin Polymerization, and Process for Production of Olefin Polymers with the Same | TOHO TITANIUM CO., LTD. (JP) | 2012-03-01 | — | — | US | disclosed |
| US-20100190942-A1 | AMINOSILANE COMPOUNDS, CATALYST COMPONENTS AND CATALYSTS FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS WITH THE SAME | TOHO CATALYST CO., LTD. (JP) | 2010-07-29 | — | — | US | disclosed |
| EP-1908767-A1 | AMINOSILANE COMPOUNDS, CATALYST COMPONENTS AND CATALYSTS FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS WITH THE SAME | Toho Catalyst Co., Ltd. (JP) | 2008-04-09 | — | — | EP | disclosed |