Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 10/20 | 0.61 |
| ▸ | GNAO1 | P09471 | 10/20 | 0.61 |
| ▸ | GNAI1 | P63096 | 10/20 | 0.61 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6944193 | 0.93 | GNAO1 (0.66) | GNAI3GNAO1GNAI1SPHK1ACE2 | |
| SCHEMBL7227721 | 0.91 | GNAO1 (0.74) | GNAI3GNAO1GNAI1SPHK1 | |
| SCHEMBL7078379 | 0.91 | GNAO1 (0.74) | GNAI3GNAO1GNAI1SPHK1 | |
| SCHEMBL6943797 | 0.89 | GNAO1 (0.66) | GNAI3GNAO1GNAI1SPHK1ACE2 | |
| SCHEMBL6941401 | 0.89 | GNAI3 (0.55) | GNAI3GNAO1GNAI1SPHK1ACE2 | |
| SCHEMBL6942008 | 0.88 | GNAO1 (0.74) | GNAI3GNAO1GNAI1SPHK1 | |
| SCHEMBL6945499 | 0.86 | GNAI3 (0.61) | GNAI3GNAO1GNAI1SPHK1ACE2 | |
| SCHEMBL6943963 | 0.83 | GNAI3 (0.47) | GNAI3GNAO1GNAI1SPHK1CARM1 | |
| SCHEMBL13822725 | 0.82 | ACE2 (0.48) | GNAI3GNAO1GNAI1ACE2PAOX | |
| SCHEMBL6941884 | 0.81 | GNAO1 (0.81) | GNAI3GNAO1GNAI1SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6642231-B2 | Antineoplastic agents, treatment for neuronal injury and degeneration | AVENTIS PHARMACEUTICALS INC. | 2003-11-04 | — | — | US | disclosed |