Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GLA | P06280 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | CASP1 | P29466 | 3/20 | 0.35 |
| ▸ | CASP7 | P55210 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8022206 | 0.69 | ALDH1A1 (0.46) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL11041869 | 0.62 | FFAR3 (0.33) | KDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL7199959 | 0.62 | ALDH1A1 (0.33) | ALDH1A1POLB | |
| SCHEMBL12263601 | 0.59 | — | — | |
| SCHEMBL28921336 | 0.58 | TP53 (0.30) | — | |
| SCHEMBL14580924 | 0.58 | — | — | |
| SCHEMBL23183224 | 0.57 | — | — | |
| Hydrochloric Acid SCHEMBL7212773 | 0.56 | BLM (0.40) | HSD17B10KMT2A | |
| SCHEMBL7221870 | 0.56 | KDM4E (0.54) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL16005167 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6566359-B1 | For use as platelet- activating factor antagonists, inhibitors of certain protein kinases, transcriptional inhibitors of COX-2(cyclooxygenase-2) expression, and as agents in protecting brain tissue from injuries related to trauma | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2003-05-20 | — | — | US | disclosed |