Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.52 |
| ▸ | YTHDC1 | Q96MU7 | 4/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | PDE1A | P54750 | 1/20 | 0.43 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.43 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6941325 | 0.88 | YTHDC1 (0.56) | ADORA3YTHDC1HDAC1CDK1MAPT | |
| SCHEMBL7227927 | 0.84 | CDK1 (0.61) | ADORA3CDK1MAPTCCNE2CCNE1 | |
| SCHEMBL6817859 | 0.78 | CDK1 (0.74) | YTHDC1HDAC1CDK1ADORA2ACCNE2 | |
| SCHEMBL6152650 | 0.76 | CTSL (0.69) | HDAC1CDK1ADORA2ACCNE2CCNE1 | |
| SCHEMBL786378 | 0.75 | YTHDC1 (0.57) | ADORA3YTHDC1CDK1MAPTADORA2A | |
| SCHEMBL6820865 | 0.75 | PPARG (0.65) | ADORA3ADORA2APPARGADORA1 | |
| SCHEMBL6944109 | 0.74 | CCNE2 (0.76) | YTHDC1HDAC1CDK1ADORA2ACCNE2 | |
| SCHEMBL17628578 | 0.74 | CDK1 (0.65) | YTHDC1HDAC1CDK1ADORA2ACCNE2 | |
| SCHEMBL6945059 | 0.74 | CCNE2 (0.57) | YTHDC1HDAC1CDK1ADORA2ACCNE2 | |
| SCHEMBL17639878 | 0.73 | PDE2A (0.58) | HDAC1CDK1ADORA2APPARGCCNE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6642231-B2 | Antineoplastic agents, treatment for neuronal injury and degeneration | AVENTIS PHARMACEUTICALS INC. | 2003-11-04 | — | — | US | disclosed |