Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6974364 | 0.93 | LMNA (0.41) | RPS6KB1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7221946 | 0.92 | RPS6KB1 (0.47) | RPS6KB1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7220276 | 0.90 | LMNA (0.46) | RPS6KB1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7220070 | 0.89 | ALDH1A1 (0.41) | RPS6KB1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7221526 | 0.89 | RPS6KB1 (0.41) | RPS6KB1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7226495 | 0.89 | DRD3 (0.48) | RPS6KB1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7219802 | 0.87 | ALDH1A1 (0.41) | LMNAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL7220757 | 0.86 | ALDH1A1 (0.41) | LMNAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL7220990 | 0.86 | RPS6KB1 (0.47) | RPS6KB1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7219490 | 0.85 | LMNA (0.47) | RPS6KB1LMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6566362-B2 | Use as topical antibiotics | AVENTIS PHARMA S.A. (FR) | 2003-05-20 | — | — | US | disclosed |
| US-20020137741-A1 | Benzo[f]naphthyridine derivatives, their preparation and compositions containing them | AVENTIS PHARMA S.A. (FR) | 2002-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020137741-A1 | Benzo[f]naphthyridine derivatives, their preparation and compositions containing them | KCNQ2, KCNQ1, KCNQ4 | RPS6KB1 2005/4885LMNA 182/4885MEN1 2544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.