SCHEMBL7228258

SCHEMBL7228258

O=P(O)(O)C(c1ccccc1)c1ccc(F)cc1

nearest known ligand 0.69

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ACP3 P15309 11/20 0.69
SRC P12931 1/20 0.52
NPC1 O15118 1/20 0.45
ALDH1A1 P00352 2/20 0.44
GAA P10253 1/20 0.44
CA12 O43570 1/20 0.44
MMP2 P08253 1/20 0.44
USP2 O75604 1/20 0.44
LMNA P02545 1/20 0.44
HPGD P15428 1/20 0.44
HTT P42858 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
PGK1 P00558 1/20 0.43
PGK2 P07205 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL777805 0.92 ACP3 (0.57) ACP3SRCCA12MMP2PGK1
SCHEMBL232244 0.87 ACP3 (0.79) ACP3SRCPGK1PGK2
Hydrochloric Acid SCHEMBL1133241 0.85 ACP3 (0.76) ACP3SRC
SCHEMBL776850 0.82 ACP3 (0.51) ACP3SRCALDH1A1GAACA12
SCHEMBL16859931 0.80 ACP3 (0.71) ACP3SRCCA12LMNA
Phenol SCHEMBL4616870 0.79 ACP3 (0.68) ACP3SRCCA12PGK1PGK2
SCHEMBL777888 0.77 ACP3 (0.64) ACP3SRCGAAPGK1PGK2
SCHEMBL8158040 0.77 ACP3 (0.65) ACP3SRC
SCHEMBL8158042 0.77 ACP3 (0.65) ACP3SRC
SCHEMBL778799 0.76 ACP3 (0.56) ACP3CA12MMP2PGK1PGK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6630607-B2 Electrophotography MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2003-10-07 US disclosed
US-20020147347-A1 Aromatic methylidene compounds, aromatic aldehyde compounds and methylstyryl compounds used to prepare the methylidene compounds, and methods for preparing these compounds MATSUSHITA ELECTIRC INDUSTRIAL CO., LTD. 2002-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020147347-A1 Aromatic methylidene compounds, aromatic aldehyde compounds and methylstyryl compounds used to prepare the methylidene compounds, and methods for preparing these compounds MCCC2, RNF31, PRMT1 ACP3 4674/4885SRC 2572/4885NPC1 1272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.