Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.40 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4375606 | 0.84 | PARP1 (0.56) | PKMKDM4EHTTPARP1MEN1 | |
| SCHEMBL20659172 | 0.79 | HTT (0.50) | KDM4EHTTPARP1MEN1KMT2A | |
| SCHEMBL22572715 | 0.77 | HTT (0.49) | PKMKDM4EHTTPARP1MEN1 | |
| SCHEMBL20659165 | 0.73 | GRIN2B (0.46) | KDM4EHTTPARP1MEN1KMT2A | |
| SCHEMBL3096979 | 0.72 | PARP1 (0.56) | PKMKDM4EHTTPARP1MEN1 | |
| SCHEMBL1651203 | 0.71 | HCAR2 (0.67) | HCAR2 | |
| SCHEMBL13130693 | 0.71 | HCAR2 (0.55) | HCAR2 | |
| SCHEMBL5700540 | 0.71 | HCAR2 (0.55) | HCAR2 | |
| SCHEMBL11818982 | 0.70 | PKM (0.64) | HCAR2PKMKDM4EPARP1MEN1 | |
| SCHEMBL16951392 | 0.70 | PARP1 (0.54) | PKMKDM4EHTTPARP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6573275-B1 | Insecticidal compositions comprising and to methods of combatting and controlling insect pests therewith. | SYNGENTA LIMITED (GB) | 2003-06-03 | — | — | US | disclosed |