Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 2/20 | 0.53 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.33 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13189787 | 0.79 | CPA1 (0.39) | CPA1 | |
| SCHEMBL27907711 | 0.79 | CPA1 (0.52) | CPA1KMT2AMEN1LMNA | |
| SCHEMBL1008129 | 0.76 | — | — | |
| SCHEMBL15374285 | 0.75 | CPA1 (0.43) | CPA1SLC7A5ALDH1A1LMNAMAPT | |
| SCHEMBL15374287 | 0.75 | CPA1 (0.43) | CPA1SLC7A5ALDH1A1LMNAMAPT | |
| SCHEMBL9851962 | 0.74 | CHRM1 (0.48) | CPA1ALDH1A1SLC1A3SLC1A2MAPT | |
| Hydrochloric Acid SCHEMBL11628885 | 0.74 | ALDH1A1 (0.41) | CPA1ALDH1A1SLC1A3SLC1A2KMT2A | |
| SCHEMBL2724137 | 0.74 | CPA1 (0.50) | CPA1RNPEPSLC7A5ALDH1A1SLC1A3 | |
| SCHEMBL27812316 | 0.74 | CPA1 (0.50) | CPA1RNPEPSLC7A5ALDH1A1SLC1A3 | |
| Nitromethane SCHEMBL28456989 | 0.73 | ALDH1A1 (0.39) | CPA1ALDH1A1SLC1A3SLC1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146991-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| CN-109563509-B | Reduced size self-delivering nucleic acid compounds targeting long non-coding RNAs | 菲奥医药公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-114727974-A | HDAC6 inhibitors and uses thereof | 艾科尼佐治疗股份有限公司 | 2022-07-08 | — | — | CN | disclosed |
| EP-3737362-A1 | COMBINATION OF A SELECTIVE HISTONE DEACETYLASE 3 (HDAC3) INHIBITOR AND AN IMMUNOTHERAPY AGENT FOR THE TREATMENT OF CANCER | KDAC THERAPEUTICS, INC. (US) | 2020-11-18 | — | — | EP | disclosed |
| EP-3481830-A1 | BICYCLIC UREA KINASE INHIBITORS AND USES THEREOF | The Broad Institute, Inc. (US) | 2019-05-15 | — | — | EP | disclosed |
| WO-2018009544-A1 | BICYCLIC UREA KINASE INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2018-01-11 | — | — | WO | disclosed |
| EP-2968274-A1 | MEROPENEM DERIVATIVES AND USES THEREOF | Kala Pharmaceuticals, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014144285-A1 | MEROPENEM DERIVATIVES AND USES THEREOF | KALA PHARMACEUTICALS, INC. (US) | 2014-09-18 | — | — | WO | disclosed |
| WO-2012027555-A2 | GLYCATED CD59 PEPTIDES, THEIR PREPARATION, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-03-01 | — | — | WO | disclosed |
| EP-1888581-A2 | HIV-INTEGRASE INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006125048-A2 | HIV-INTEGRASE INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2006-11-23 | — | — | WO | disclosed |