Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 5/20 | 0.46 |
| ▸ | GABRP | O00591 | 2/20 | 0.45 |
| ▸ | GABRD | O14764 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.45 |
| ▸ | GABRE | P78334 | 2/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27597211 | 0.79 | CPA1 (0.37) | MEN1LMNABLMHBBKMT2A | |
| SCHEMBL8371859 | 0.78 | CPA1 (0.48) | MEN1LMNABLMHBBKMT2A | |
| SCHEMBL4919499 | 0.77 | GABRP (0.62) | LMNAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11442621 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL16667716 | 0.74 | GABRP (0.59) | LMNAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL14360308 | 0.74 | GABRP (0.59) | LMNAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3331716 | 0.74 | GABRP (0.48) | MEN1LMNABLMHBBKMT2A | |
| SCHEMBL2128235 | 0.74 | CPA1 (0.44) | HIF1ACPA1 | |
| SCHEMBL27597210 | 0.73 | ADRA2A (0.38) | BLMCPA1MAPT | |
| SCHEMBL17318330 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146991-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| EP-3737362-A1 | COMBINATION OF A SELECTIVE HISTONE DEACETYLASE 3 (HDAC3) INHIBITOR AND AN IMMUNOTHERAPY AGENT FOR THE TREATMENT OF CANCER | KDAC THERAPEUTICS, INC. (US) | 2020-11-18 | — | — | EP | disclosed |
| CN-109803962-A | Modulators of cystic fibrosis transmembrane conductance regulator proteins, pharmaceutical compositions, methods of treatment, and methods for making the modulators | 弗特克斯药品有限公司 | 2019-05-24 | — | — | CN | disclosed |
| EP-3481830-A1 | BICYCLIC UREA KINASE INHIBITORS AND USES THEREOF | The Broad Institute, Inc. (US) | 2019-05-15 | — | — | EP | disclosed |
| CN-109195996-A | Modular synthesis method of N-glycan and array thereof | 中央研究院 | 2019-01-11 | — | — | CN | disclosed |
| WO-2018009544-A1 | BICYCLIC UREA KINASE INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2018-01-11 | — | — | WO | disclosed |
| CN-105481766-A | Quinocide and preparation method of hydrochloride thereof | HIGH & NEW TECH RES CENTER OF HENAN ACAD OF SCIENCES | 2016-04-13 | — | — | CN | disclosed |
| EP-2968274-A1 | MEROPENEM DERIVATIVES AND USES THEREOF | Kala Pharmaceuticals, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014144285-A1 | MEROPENEM DERIVATIVES AND USES THEREOF | KALA PHARMACEUTICALS, INC. (US) | 2014-09-18 | — | — | WO | disclosed |
| WO-2012027555-A2 | GLYCATED CD59 PEPTIDES, THEIR PREPARATION, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-03-01 | — | — | WO | disclosed |
| EP-2205074-A2 | MOENOMYCIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-07-14 | — | — | EP | disclosed |
| WO-2009046314-A2 | MOENOMYCIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-04-09 | — | — | WO | disclosed |
| WO-2008124571-A2 | ANTI-VIRAL COMPOUNDS, COMPOSITIONS AND METHODS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2008-10-16 | — | — | WO | disclosed |
| WO-2008028057-A2 | SHIKIMIC ACID-DERIVED COMPOUNDS FOR INHIBITION AND DETECTION OF AURORA A-ASSOCIATED TUMORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2008-03-06 | — | — | WO | disclosed |
| EP-1888581-A2 | HIV-INTEGRASE INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006125048-A2 | HIV-INTEGRASE INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2006-11-23 | — | — | WO | disclosed |