Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7228768 | 1.00 | CA2 (0.35) | CA2CHKAKDM4ESIGMAR1 | |
| SCHEMBL7230613 | 0.98 | CA2 (0.32) | CA2CHKASIGMAR1 | |
| SCHEMBL7230608 | 0.98 | CA2 (0.32) | CA2CHKASIGMAR1 | |
| SCHEMBL7224065 | 0.93 | SIGMAR1 (0.33) | SIGMAR1 | |
| SCHEMBL7228771 | 0.92 | — | — | |
| SCHEMBL7228778 | 0.92 | — | — | |
| SCHEMBL7229972 | 0.90 | — | — | |
| SCHEMBL7229061 | 0.89 | CYP2B6 (0.31) | — | |
| SCHEMBL7229066 | 0.89 | CYP2B6 (0.31) | — | |
| SCHEMBL7221803 | 0.89 | CYP2B6 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6552226-B1 | Rapid; low temperature; one pot synthesis; reduced catalytic quantities of such as lewis acid and tertiary amine; entiomerically pure products | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-04-22 | — | — | US | disclosed |