⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11364735 | 0.79 | — | — | |
| SCHEMBL133807 | 0.75 | — | — | |
| SCHEMBL28126995 | 0.72 | — | — | |
| SCHEMBL26185927 | 0.70 | ALOX5 (0.44) | — | |
| SCHEMBL28759050 | 0.70 | — | — | |
| SCHEMBL28247080 | 0.70 | — | — | |
| SCHEMBL929876 | 0.68 | — | — | |
| SCHEMBL3084323 | 0.68 | — | — | |
| SCHEMBL28093596 | 0.68 | — | — | |
| SCHEMBL48448 | 0.66 | ALOX15 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116171153-A | Compositions for modulating splicing | 斯基霍克疗法公司 | 2023-05-26 | — | — | CN | disclosed |
| CN-114126613-A | Methods and compositions for modulating splicing | 斯基霍克疗法公司 | 2022-03-01 | — | — | CN | disclosed |
| US-6534518-B1 | Phosphodiesterase inhibitors for respiratory system disorders | ALTANA PHARMA AG (DE) | 2003-03-18 | — | — | US | disclosed |
| EP-1163226-A1 | POLYSUBSTITUTED 6-PHENYLPHENANTHRIDINES WITH PDE-IV INHIBITING ACTIVITY | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 2001-12-19 | — | — | EP | disclosed |
| WO-2000042018-A1 | POLYSUBSTITUTED 6-PHENYLPHENANTHRIDINES WITH PDE-IV INHIBITING ACTIVITY | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-07-20 | — | — | WO | disclosed |