SCHEMBL7229115

SCHEMBL7229115

COc1nc(C)nc(F)c1C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.33
PKM P14618 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11036145 0.76 MAPT (0.32) RXFP1
SCHEMBL7221160 0.74 KDM4E (0.31) DYRK1A
SCHEMBL22042740 0.72 PIK3R1 (0.31)
SCHEMBL22042736 0.72 GAA (0.35)
SCHEMBL29635367 0.72 GAA (0.35)
SCHEMBL25140912 0.71
SCHEMBL9344676 0.71 DYRK1A (0.34) DYRK1APKMRXFP1
SCHEMBL11036785 0.71 NPC1 (0.47) PKM
SCHEMBL22042753 0.71 KMT2A (0.33)
SCHEMBL12649521 0.71 DYRK1A (0.39) DYRK1APKMRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6551682-B1 Proper tracking error signals to be adapted to high density information recording and has various characteristics MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2003-04-22 US disclosed