Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3674088 | 0.84 | PKM (0.37) | DYRK1APKMRXFP1PIM1CDK9 | |
| SCHEMBL11555941 | 0.77 | PKM (0.34) | DYRK1APKMRXFP1PIM1CDK9 | |
| SCHEMBL16016862 | 0.74 | LMNA (0.41) | DYRK1APKMRXFP1PIM1CDK9 | |
| SCHEMBL12649521 | 0.74 | DYRK1A (0.39) | DYRK1APKMRXFP1 | |
| SCHEMBL7229115 | 0.71 | DYRK1A (0.33) | DYRK1APKMRXFP1 | |
| SCHEMBL15443926 | 0.68 | DYRK1A (0.36) | DYRK1APKMRXFP1 | |
| SCHEMBL9124920 | 0.67 | SMN1; SMN2 (0.36) | RXFP1 | |
| SCHEMBL27083057 | 0.67 | HSD17B10 (0.33) | — | |
| SCHEMBL11625999 | 0.67 | HSD17B10 (0.31) | — | |
| SCHEMBL3667991 | 0.67 | CCNA2 (0.34) | DYRK1APKMRXFP1PIM1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378089-B1 | Method for the preparation of 2-amino-4-fluoropyrimidine derivatives | BASF AG (DE) | 1994-06-29 | — | — | EP | disclosed |
| EP-0378089-A1 | Method for the preparation of 2-amino-4-fluoropyrimidine derivatives | BASF Aktiengesellschaft (DE) | 1990-07-18 | — | — | EP | disclosed |