SCHEMBL7229172

SCHEMBL7229172

CCCC(F)=C(F)c1ccc(CCc2ccc(CCC)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.46
PLK1 P53350 1/20 0.44
THRB P10828 2/20 0.43
LPL P06858 1/20 0.41
LIPG Q9Y5X9 1/20 0.41
ALDH1A1 P00352 3/20 0.40
POLB P06746 3/20 0.40
CTDSP1 Q9GZU7 3/20 0.40
GAA P10253 3/20 0.40
KDM4E B2RXH2 1/20 0.40
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
KMT2A Q03164 2/20 0.39
MAPT P10636 1/20 0.39
LMNA P02545 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ESR1 P03372 2/20 0.38
ESR2 Q92731 2/20 0.38
THRA P10827 1/20 0.38
S1PR1 P21453 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7229164 1.00 L3MBTL1 (0.46) L3MBTL1PLK1THRBLPLLIPG
SCHEMBL7229170 1.00 L3MBTL1 (0.46) L3MBTL1PLK1THRBLPLLIPG
SCHEMBL7763554 0.93 L3MBTL1 (0.44) L3MBTL1PLK1THRBLPLLIPG
SCHEMBL7763561 0.93 L3MBTL1 (0.44) L3MBTL1PLK1THRBLPLLIPG
SCHEMBL7763556 0.93 L3MBTL1 (0.44) L3MBTL1PLK1THRBLPLLIPG
SCHEMBL7237534 0.89 L3MBTL1 (0.44) L3MBTL1PLK1THRBLPLLIPG
SCHEMBL7237536 0.89 L3MBTL1 (0.44) L3MBTL1PLK1THRBLPLLIPG
SCHEMBL7237539 0.89 L3MBTL1 (0.44) L3MBTL1PLK1THRBLPLLIPG
SCHEMBL7233401 0.89 CYP1A2 (0.38) L3MBTL1PLK1THRBNPC1RAB9A
SCHEMBL7233398 0.89 CYP1A2 (0.38) L3MBTL1PLK1THRBNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6623810-B2 Refractive index anisotropy SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-09-23 US disclosed
US-20010050353-A1 Phenylacetylene compound, liquid crystal composition, and liquid crystal element produced with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-12-13 US disclosed
EP-0781827-B1 Liquid crystal mixture and liquid crystal device comprising the same SUMITOMO CHEMICAL CO (JP) 2001-06-13 EP disclosed
US-6149837-A SUBSTITUTED 1,4-BIS(SUBSTITUED PHENYLACETYLENE)BENZENE WHERE AT LEAST ONE RING HAS AN ALKYL ATTACHMENT, HAS A LARGE ANISOTROPY OF REFRACTIVE INDEX, TENDS TO BE MIXED WITH OTHER LIQUID CRYSTALS, IS LIGHT STABLE; LIQUID CRYSTAL ELEMENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-11-21 US disclosed
EP-0781827-A1 Liquid crystal mixture and liquid crystal device comprising the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-07-02 EP disclosed