SCHEMBL7763554

SCHEMBL7763554

CCC/C(F)=C(\F)c1ccc(CCCc2ccc(CCC)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.44
THRB P10828 3/20 0.43
THRA P10827 2/20 0.43
PLK1 P53350 2/20 0.42
RARB P10826 4/20 0.40
LPL P06858 1/20 0.39
LIPG Q9Y5X9 1/20 0.39
TNNC1 P63316 5/20 0.38
SGPL1 O95470 1/20 0.38
S1PR4 O95977 1/20 0.38
S1PR1 P21453 1/20 0.38
GPR183 P32249 1/20 0.38
CERS2 Q96G23 1/20 0.38
S1PR3 Q99500 1/20 0.38
S1PR5 Q9H228 1/20 0.38
POLB P06746 1/20 0.38
CTDSP1 Q9GZU7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7763561 1.00 L3MBTL1 (0.44) L3MBTL1THRBTHRAPLK1RARB
SCHEMBL7763556 1.00 L3MBTL1 (0.44) L3MBTL1THRBTHRAPLK1RARB
SCHEMBL7229164 0.93 L3MBTL1 (0.46) L3MBTL1THRBTHRAPLK1LPL
SCHEMBL7229170 0.93 L3MBTL1 (0.46) L3MBTL1THRBTHRAPLK1LPL
SCHEMBL7229172 0.93 L3MBTL1 (0.46) L3MBTL1THRBTHRAPLK1LPL
SCHEMBL7238691 0.88 THRA (0.53) THRBTHRARARBTNNC1SGPL1
SCHEMBL7238683 0.88 THRA (0.53) THRBTHRARARBTNNC1SGPL1
SCHEMBL7238695 0.88 THRA (0.53) THRBTHRARARBTNNC1SGPL1
SCHEMBL7239405 0.87 THRA (0.55) THRBTHRARARBTNNC1SGPL1
SCHEMBL7239403 0.87 THRA (0.55) THRBTHRARARBTNNC1SGPL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0781827-B1 Liquid crystal mixture and liquid crystal device comprising the same SUMITOMO CHEMICAL CO (JP) 2001-06-13 EP disclosed
EP-0781827-A1 Liquid crystal mixture and liquid crystal device comprising the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-07-02 EP disclosed