Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.45 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.45 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.45 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL28916613 | 1.00 | LMNA (0.45) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL28778164 | 0.93 | LMNA (0.39) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Adipic Acid SCHEMBL906129 | 0.91 | LMNA (0.50) | LMNAALDH1A1SLC22A6TSHRFOLH1 | |
| Adipic Acid SCHEMBL29427201 | 0.91 | LMNA (0.50) | LMNAALDH1A1SLC22A6TSHRFOLH1 | |
| Glutarate SCHEMBL28487046 | 0.91 | SLC22A6 (0.50) | LMNAMAPK1SLC22A6TSHRNFKB1 | |
| Glutarate SCHEMBL9485824 | 0.91 | SLC22A6 (0.50) | LMNAMAPK1SLC22A6TSHRNFKB1 | |
| SCHEMBL27786269 | 0.89 | TSHR (0.36) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Octanedioate SCHEMBL1394807 | 0.89 | TSHR (0.52) | LMNAOR51E2ALDH1A1SLC22A6TSHR | |
| Azelaic Acid SCHEMBL28918234 | 0.89 | TSHR (0.52) | LMNAOR51E2ALDH1A1SLC22A6TSHR | |
| Octanedioate SCHEMBL6037661 | 0.89 | TSHR (0.52) | LMNAOR51E2ALDH1A1SLC22A6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119688660-B | Double-probe detection reagent for detecting methicillin-resistant staphylococcus aureus and preparation method thereof | 合肥工业大学 | 2025-06-13 | — | — | CN | claimed |
| CN-120121832-A | Double-probe detection reagent for detecting salmonella typhimurium and preparation method thereof | 合肥工业大学 | 2025-06-10 | — | — | CN | claimed |
| CN-119688660-A | Double-probe detection reagent for detecting methicillin-resistant staphylococcus aureus and preparation method thereof | 合肥工业大学 | 2025-03-25 | — | — | CN | claimed |
| CN-114438047-B | Method for preparing polyethylene glycol modified urate oxidase | 重庆派金生物科技有限公司 | 2024-11-22 | — | — | CN | claimed |
| CN-118453890-A | Composition for improving stability of polyethylene glycol asparaginase, pharmaceutical composition and application thereof | 重庆派金生物科技有限公司 | 2024-08-09 | — | — | CN | claimed |
| US-11857693-B2 | Medical sealant glue capable of promoting wound healing and preparation method thereof | SHANDONG BRANDEN MEDICAL DEVICE CO., LTD (CN) | 2024-01-02 | — | — | US | claimed |
| CN-116966279-A | Covalently modified recombinant phenylalanine lyase enteric-coated preparation and application thereof | 重庆派金生物科技有限公司 | 2023-10-31 | — | — | CN | claimed |
| CN-115869456-A | Preparation of in-situ gelation anti-swelling enhanced tissue adhesive material | 上海其胜生物制剂有限公司 | 2023-03-31 | — | — | CN | claimed |
| WO-2022095974-A1 | METHOD FOR PREPARING POLYETHYLENE GLYCOL-MODIFIED URATE OXIDASE | 杭州远大生物制药有限公司 | 2022-05-12 | — | — | WO | claimed |
| CN-114438047-A | Method for preparing polyethylene glycol modified urate oxidase | 重庆派金生物科技有限公司 | 2022-05-06 | — | — | CN | claimed |
| WO-2020134757-A1 | MEDICAL SEALING GLUE CAPABLE OF PROMOTING WOUND HEALING AND PREPARATION METHOD THEREFOR | 山东百多安医疗器械股份有限公司 | 2020-07-02 | — | — | WO | claimed |
| US-9585988-B2 | Anchorage devices comprising an active pharmaceutical ingredient | TYRX, INC. (US) | 2017-03-07 | — | — | US | claimed |
| EP-1632508-B1 | New ethylene copolymeres, compositions comprising the same and treatment method | OREAL (FR) | 2011-01-05 | — | — | EP | claimed |
| EP-1632508-A2 | New ethylene copolymeres, compositions comprising the same and treatment method | L'OREAL (FR) | 2006-03-08 | — | — | EP | claimed |
| US-20060018863-A1 | Novel ethylenic copolymers, compositions and methods of the same | L'OREAL S.A. (FR) | 2006-01-26 | — | — | US | claimed |
| US-12447242-B2 | Hemostatic devices and methods of use | MEDTRONIC, INC. (US) | 2025-10-21 | — | — | US | disclosed |
| EP-3452124-B1 | HEMOSTATIC DEVICES AND METHODS OF USE | MEDTRONIC INC (US) | 2025-10-08 | — | — | EP | disclosed |
| US-20080132922-A1 | Mesh Pouches for Implantable Medical Devices | TYRX PHARMA, INC. (US) | 2008-06-05 | — | — | US | disclosed |
| US-20070198040-A1 | Temporarily Stiffened Mesh Prostheses | TYRX PHARMA INC. (US) | 2007-08-23 | — | — | US | disclosed |
| US-6319674-B1 | IMMOBILIZATION ON SURFACE WITH AMINES AND HYDROXY GROUPS | AGILENT TECHNOLOGIES, INC. | 2001-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060018863-A1 | Novel ethylenic copolymers, compositions and methods of the same | ERCC1, ERCC5, ACP1 | LMNA 2993/4885EGLN1 483/4885ALKBH5 584/4885 |
| US-12447242-B2 | Hemostatic devices and methods of use | HABP2, PLAT, F2 | LMNA 624/4885EGLN1 82/4885ALKBH5 2923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.