Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | RECQL | P46063 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19626587 | 0.85 | MAPT (0.52) | GAARECQLALDH1A1MAPTKDM4E | |
| SCHEMBL3271623 | 0.84 | GAA (0.60) | GAAGRM5 | |
| SCHEMBL8700799 | 0.82 | KDM4E (0.68) | GAARECQLALDH1A1MAPTKDM4E | |
| SCHEMBL1764515 | 0.80 | RAB9A (0.64) | GAARECQLALDH1A1MAPTKDM4E | |
| SCHEMBL1764772 | 0.79 | RECQL (0.58) | GAARECQLALDH1A1MAPTKDM4E | |
| SCHEMBL19196704 | 0.79 | KDM4E (0.64) | GAARECQLALDH1A1MAPTKDM4E | |
| SCHEMBL1765099 | 0.78 | ALDH1A1 (0.58) | GAARECQLALDH1A1MAPTKDM4E | |
| SCHEMBL480736 | 0.78 | MAPT (0.68) | ALDH1A1MAPTKDM4EPOLBHPGD | |
| SCHEMBL21230568 | 0.78 | GAA (0.53) | GAARECQLALDH1A1MAPTKDM4E | |
| SCHEMBL13997536 | 0.76 | MAPT (0.60) | GAARECQLALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6573275-B1 | Insecticidal compositions comprising and to methods of combatting and controlling insect pests therewith. | SYNGENTA LIMITED (GB) | 2003-06-03 | — | — | US | disclosed |