Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 2/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | PGK2 | P07205 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10472538 | 0.73 | ALDH1A1 (0.64) | LMNAALDH1A1TSHRHMGCRCHRM1 | |
| SCHEMBL606619 | 0.73 | ALDH1A1 (0.64) | LMNAALDH1A1TSHRHMGCRCHRM1 | |
| SCHEMBL10453248 | 0.73 | ALDH1A1 (0.64) | LMNAALDH1A1TSHRHMGCRCHRM1 | |
| SCHEMBL2372647 | 0.72 | LMNA (0.50) | LMNAALDH1A1TSHRFDPSPGK1 | |
| SCHEMBL7654249 | 0.69 | LMNA (0.45) | LMNAALDH1A1TSHRFDPSPGK1 | |
| SCHEMBL1336319 | 0.69 | LMNA (0.45) | LMNAALDH1A1TSHRFDPSPGK1 | |
| SCHEMBL29153273 | 0.69 | TSHR (0.50) | LMNAALDH1A1TSHRHMGCRCHRM1 | |
| SCHEMBL8838818 | 0.69 | LMNA (0.45) | LMNAALDH1A1TSHRFDPSPGK1 | |
| SCHEMBL2102481 | 0.67 | TSHR (0.56) | ALDH1A1TSHRHMGCRCHRM1TBXA2R | |
| SCHEMBL1953738 | 0.67 | TSHR (0.56) | ALDH1A1TSHRHMGCRCHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027642-A1 | BALANCED FOUR-STEP PATHWAYS TO RENEWABLE BUTANOLS | GEVO, INC. (US) | 2012-03-01 | — | — | WO | disclosed |