Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.43 |
| ▸ | PGK1 | P00558 | 3/20 | 0.42 |
| ▸ | PGK2 | P07205 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7454684 | 0.97 | ADORA3 (0.46) | ADORA3ADORA2AADORA1ADORA2BPGK1 | |
| Formic Acid SCHEMBL7222865 | 0.93 | PGK1 (0.44) | ADORA3ADORA2AADORA1ADORA2BPGK1 | |
| SCHEMBL7229734 | 0.92 | PGK1 (0.39) | ADORA3ADORA2AADORA1ADORA2BPGK1 | |
| Formic Acid SCHEMBL7229780 | 0.92 | ADORA3 (0.44) | ADORA3ADORA2AADORA1ADORA2BPGK1 | |
| SCHEMBL7455516 | 0.90 | PGK1 (0.46) | ADORA3ADORA2AADORA1ADORA2BPGK1 | |
| SCHEMBL7463422 | 0.89 | ADORA3 (0.53) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL5086112 | 0.89 | ADORA3 (0.47) | ADORA3ADORA2AADORA1ADORA2BPGK1 | |
| Formic Acid SCHEMBL7231329 | 0.89 | PGK1 (0.54) | ADORA3ADORA2AADORA1ADORA2BPGK1 | |
| Acetic Acid SCHEMBL7223368 | 0.88 | ADORA3 (0.51) | ADORA3ADORA2AADORA1ADORA2B | |
| Formic Acid SCHEMBL7223839 | 0.88 | PGK1 (0.48) | ADORA3ADORA2AADORA1ADORA2BPGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6528494-B2 | Antiinflammatory agents | COX BRIAN (GB) | 2003-03-04 | — | — | US | disclosed |
| EP-0948509-B1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2002-10-16 | — | — | EP | disclosed |
| US-6426337-B1 | ANTIINFLAMMATORY AGENTS | SMITHKLINE BEECHAM CORPORATION | 2002-07-30 | — | — | US | disclosed |