Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4447859 | 0.89 | CYP3A4 (0.59) | ALDH1A1HPGDKDM4EHSD17B10KMT2A | |
| SCHEMBL3154846 | 0.89 | CYP3A4 (0.59) | ALDH1A1HPGDKDM4EHSD17B10KMT2A | |
| SCHEMBL5563991 | 0.81 | RAB9A (0.58) | ALDH1A1HPGDKDM4EHSD17B10KMT2A | |
| SCHEMBL5563987 | 0.81 | RAB9A (0.58) | ALDH1A1HPGDKDM4EHSD17B10KMT2A | |
| SCHEMBL7492 | 0.78 | ATM (0.55) | ALDH1A1HPGDKDM4EHSD17B10KMT2A | |
| SCHEMBL11790505 | 0.77 | RAB9A (0.54) | ALDH1A1HPGDKDM4EHSD17B10KMT2A | |
| SCHEMBL11790484 | 0.77 | RAB9A (0.54) | ALDH1A1HPGDKDM4EHSD17B10KMT2A | |
| SCHEMBL19215448 | 0.76 | ALDH1A1 (0.57) | ALDH1A1HPGDKDM4EHSD17B10KMT2A | |
| SCHEMBL15748984 | 0.74 | RAB9A (0.48) | ALDH1A1HPGDKDM4EHSD17B10KMT2A | |
| SCHEMBL15803748 | 0.74 | ALDH1A1 (0.50) | ALDH1A1HPGDKDM4EHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6509344-B1 | A method for treating a patient having cancer, said method comprising the step of administering to the patient an effective amount of a compound according to claim 1, whereupon said patient is treated for cancer, and wherein the cancer is | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2003-01-21 | — | — | US | disclosed |