Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | GCGR | P47871 | 12/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ADCYAP1R1 | P41586 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7235710 | 0.89 | GCGR (0.61) | MAPTCYP1A2CYP3A4CYP2C19GCGR | |
| SCHEMBL2650562 | 0.86 | ALDH1A1 (0.79) | ALDH1A1MAPTL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL7239339 | 0.84 | ADCYAP1R1 (0.57) | ALDH1A1MAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7230369 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPTL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL7237620 | 0.74 | ADCYAP1R1 (0.52) | ALDH1A1MAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL2650257 | 0.73 | ALDH1A1 (0.59) | ALDH1A1MAPTL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL7230022 | 0.73 | GCGR (0.44) | KDM4EGCGRADCYAP1R1 | |
| SCHEMBL7228850 | 0.70 | GCGR (0.57) | MAPTCYP1A2CYP3A4CYP2C19GCGR | |
| SCHEMBL28743047 | 0.70 | GCGR (0.51) | GCGRADCYAP1R1 | |
| SCHEMBL3291010 | 0.69 | ALDH1A1 (0.63) | ALDH1A1MAPTL3MBTL1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |