Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCYAP1R1 | P41586 | 2/20 | 0.57 |
| ▸ | GCGR | P47871 | 14/20 | 0.53 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7235710 | 0.93 | GCGR (0.61) | ADCYAP1R1GCGRMEN1KMT2AMAPT | |
| SCHEMBL7230367 | 0.84 | ALDH1A1 (0.59) | ADCYAP1R1GCGRMEN1KMT2AMAPT | |
| SCHEMBL27517422 | 0.80 | ACHE (0.50) | ADCYAP1R1GCGRPDCD1CD274 | |
| SCHEMBL7230022 | 0.78 | GCGR (0.44) | ADCYAP1R1GCGR | |
| SCHEMBL7237620 | 0.77 | ADCYAP1R1 (0.52) | ADCYAP1R1MEN1KMT2AMAPTLMNA | |
| SCHEMBL7145109 | 0.77 | AMY1A (0.54) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL2650257 | 0.76 | ALDH1A1 (0.59) | ADCYAP1R1GCGRPDCD1CD274MEN1 | |
| SCHEMBL7239341 | 0.75 | ADCYAP1R1 (0.56) | ADCYAP1R1GCGRMAPTALDH1A1 | |
| SCHEMBL9072346 | 0.74 | ADCYAP1R1 (1.00) | ADCYAP1R1GCGR | |
| SCHEMBL9189285 | 0.73 | PTGS2 (0.60) | ADCYAP1R1GCGRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |