Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 15/20 | 0.49 |
| ▸ | MMP2 | P08253 | 9/20 | 0.49 |
| ▸ | MMP1 | P03956 | 12/20 | 0.48 |
| ▸ | MMP3 | P08254 | 10/20 | 0.48 |
| ▸ | MMP13 | P45452 | 6/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7222497 | 0.76 | MMP2 (0.64) | MMP9MMP2MMP1MMP3MMP13 | |
| SCHEMBL7231126 | 0.76 | MMP2 (0.75) | MMP9MMP2MMP1MMP3MMP13 | |
| SCHEMBL7230732 | 0.69 | MMP2 (0.66) | MMP9MMP2MMP1MMP3MMP13 | |
| SCHEMBL7233389 | 0.69 | MMP2 (0.70) | MMP9MMP2MMP1MMP3MMP13 | |
| SCHEMBL7224278 | 0.66 | MMP2 (0.61) | MMP9MMP2MMP1MMP3MMP13 | |
| SCHEMBL7224208 | 0.66 | MMP2 (0.86) | MMP9MMP2MMP1MMP3MMP13 | |
| SCHEMBL7231531 | 0.65 | MMP2 (0.59) | MMP9MMP2MMP1MMP3MMP13 | |
| SCHEMBL7229433 | 0.65 | MMP2 (0.62) | MMP9MMP2MMP1MMP3MMP13 | |
| SCHEMBL7224271 | 0.65 | MMP2 (0.67) | MMP9MMP2MMP1MMP3MMP13 | |
| SCHEMBL7231013 | 0.65 | MMP2 (0.51) | MMP9MMP2MMP1MMP3MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6605604-B1 | Tumour necrosis factor alpha release inhibitors; efficiency treatment of cancers, rheumatic diseases, arthritis, ulcers, atherosclerosis, asthma | LES LABORATOIRES SERVIER (FR) | 2003-08-12 | — | — | US | disclosed |