Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MLLT1 | Q03111 | 4/20 | 0.38 |
| ▸ | MLLT3 | P42568 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7224277 | 0.89 | USP30 (0.43) | USP30HSD17B1HSD17B2NPC1POLB | |
| SCHEMBL7223211 | 0.89 | USP30 (0.41) | USP30NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL7224212 | 0.89 | USP30 (0.41) | USP30NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL7226302 | 0.89 | NPC1 (0.52) | USP30CYP2C9NPC1POLBRAB9A | |
| SCHEMBL7225292 | 0.89 | P2RX7 (0.43) | KDM1AMAOAMAOBUSP30NPC1 | |
| SCHEMBL7071274 | 0.89 | USP30 (0.53) | USP30CYP3A4CYP2C9NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7075524 | 0.88 | USP30 (0.52) | USP30CYP3A4CYP2C9NPC1RAB9A | |
| SCHEMBL7224996 | 0.88 | USP30 (0.42) | USP30HSD17B1HSD17B2NPC1RAB9A | |
| SCHEMBL7232527 | 0.87 | USP30 (0.42) | USP30NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL7224838 | 0.87 | USP30 (0.46) | USP30CYP3A4NPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |