Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 4/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.42 |
| ▸ | TUBB | P07437 | 3/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.42 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18421247 | 0.82 | MAPT (0.42) | KDM4EPOLBPDE4APDE4BPDE4C | |
| SCHEMBL28312125 | 0.82 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL5534604 | 0.82 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL2024931 | 0.77 | CA2 (0.49) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL12626305 | 0.77 | PDE4A (0.47) | KDM4EPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9348395 | 0.74 | KDM4E (0.55) | KDM4EPOLBTUBB4ATUBBTUBA3C | |
| SCHEMBL11928777 | 0.74 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DTUBB4A | |
| SCHEMBL19014916 | 0.74 | PDE4A (0.77) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL16156475 | 0.74 | PDE4A (0.62) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL31469617 | 0.74 | PDE4A (0.57) | KDM4EPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6531469-B1 | Treatment of myocardial ischemia, chronic stable angina, unstable angina and prinzmetal's angina attacks, silent cardiac ischemia, reinfarction, reocclusion and restenosis | PIERRE FABRE MEDICAMENT (FR) | 2003-03-11 | — | — | US | disclosed |