Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7233937 | 0.89 | ALDH1A1 (0.70) | KMT2AMEN1HSD17B10ALDH1A1KDM4E | |
| SCHEMBL7234226 | 0.85 | MEN1 (0.57) | KMT2AMEN1HSD17B10ALDH1A1KDM4E | |
| SCHEMBL6794958 | 0.83 | MAPT (0.58) | KMT2AMEN1HSD17B10ALDH1A1KDM4E | |
| SCHEMBL7232816 | 0.83 | MAPT (0.58) | KMT2AMEN1HSD17B10ALDH1A1KDM4E | |
| SCHEMBL7234671 | 0.83 | KMT2A (0.60) | KMT2AMEN1HSD17B10ALDH1A1KDM4E | |
| Ammonia Solution, Strong SCHEMBL7239598 | 0.82 | MAPT (0.57) | KMT2AMEN1HSD17B10ALDH1A1KDM4E | |
| Ammonia Solution, Strong SCHEMBL7239595 | 0.82 | MAPT (0.57) | KMT2AMEN1HSD17B10ALDH1A1KDM4E | |
| SCHEMBL7233063 | 0.82 | MAPT (0.54) | KMT2AMEN1HSD17B10ALDH1A1KDM4E | |
| SCHEMBL7232704 | 0.82 | MAPT (0.54) | KMT2AMEN1HSD17B10ALDH1A1KDM4E | |
| SCHEMBL7242700 | 0.82 | HSD17B10 (0.69) | KMT2AMEN1HSD17B10ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6664271-B1 | Amide, carbamate and uredo derivatives of 3-piperidine-carboxylic acid or ester; protecting against infection by such as escherichia coli and/or actinobacillus pleuropneumoniae | ELI LILLY AND COMPANY | 2003-12-16 | — | — | US | claimed |
| WO-2000071519-A2 | IMMUNOPOTENTIATOR AGENTS | ELI LILLY AND COMPANY (US) | 2000-11-30 | — | — | WO | claimed |
| US-6664271-B1 | Amide, carbamate and uredo derivatives of 3-piperidine-carboxylic acid or ester; protecting against infection by such as escherichia coli and/or actinobacillus pleuropneumoniae | ELI LILLY AND COMPANY | 2003-12-16 | — | — | US | disclosed |