Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7232816 | 1.00 | MAPT (0.58) | MAPTPKMALDH1A1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL7239598 | 0.99 | MAPT (0.57) | MAPTPKMALDH1A1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL7239595 | 0.99 | MAPT (0.57) | MAPTPKMALDH1A1MEN1KMT2A | |
| SCHEMBL7233063 | 0.89 | MAPT (0.54) | MAPTPKMALDH1A1MEN1KMT2A | |
| SCHEMBL7232704 | 0.89 | MAPT (0.54) | MAPTPKMALDH1A1MEN1KMT2A | |
| SCHEMBL7234226 | 0.86 | MEN1 (0.57) | MAPTPKMALDH1A1MEN1KMT2A | |
| SCHEMBL7241560 | 0.84 | ALDH1A1 (0.56) | MAPTPKMALDH1A1MEN1KMT2A | |
| SCHEMBL7232184 | 0.83 | KMT2A (0.76) | ALDH1A1MEN1KMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL28630788 | 0.83 | ALDH1A1 (0.55) | MAPTPKMALDH1A1MEN1KMT2A | |
| SCHEMBL7233482 | 0.82 | ALDH1A1 (0.54) | MAPTPKMALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6664271-B1 | Amide, carbamate and uredo derivatives of 3-piperidine-carboxylic acid or ester; protecting against infection by such as escherichia coli and/or actinobacillus pleuropneumoniae | ELI LILLY AND COMPANY | 2003-12-16 | — | — | US | claimed |
| WO-2000071519-A2 | IMMUNOPOTENTIATOR AGENTS | ELI LILLY AND COMPANY (US) | 2000-11-30 | — | — | WO | claimed |
| US-20040039206-A1 | Process for resolving racemic mixtures of piperidine derivatives | MOHER ERIC DAVID (US) | 2004-02-26 | — | — | US | disclosed |
| US-6664271-B1 | Amide, carbamate and uredo derivatives of 3-piperidine-carboxylic acid or ester; protecting against infection by such as escherichia coli and/or actinobacillus pleuropneumoniae | ELI LILLY AND COMPANY | 2003-12-16 | — | — | US | disclosed |
| EP-1341762-A1 | PROCESS FOR RESOLVING RACEMIC MIXTURES OF PIPERIDINE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002068391-A1 | PROCESS FOR RESOLVING RACEMIC MIXTURES OF PIPERIDINE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2002-09-06 | — | — | WO | disclosed |
| WO-2000071519-A2 | IMMUNOPOTENTIATOR AGENTS | ELI LILLY AND COMPANY (US) | 2000-11-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040039206-A1 | Process for resolving racemic mixtures of piperidine derivatives | SRR, OPRM1, SRM | MAPT 2571/4885PKM 3192/4885ALDH1A1 1088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.