Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7229680 | 0.88 | HPGD (0.36) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7231438 | 0.86 | CHRNB2 (0.31) | SLC6A3SLC6A4 | |
| SCHEMBL7223163 | 0.84 | SLC6A3 (0.32) | KDM1ASLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7223191 | 0.84 | SLC6A3 (0.31) | KDM1ASLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7234233 | 0.83 | SLC6A3 (0.32) | KDM1ASLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7226599 | 0.83 | KDM4E (0.37) | KDM1ASLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7122334 | 0.83 | SLC6A2 (0.37) | KDM1ASLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7223423 | 0.83 | SLC6A2 (0.35) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7233475 | 0.82 | SLC6A3 (0.35) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7223916 | 0.82 | CTSC (0.35) | KDM1ASLC6A3SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |