Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GYS1 | P13807 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4398613 | 0.91 | GYS1 (0.46) | GYS1CYP1A2ALDH1A1HPGDMAOA | |
| SCHEMBL7232265 | 0.84 | CYP1A2 (0.40) | GYS1CYP1A2ALDH1A1HPGDCYP3A4 | |
| SCHEMBL4398280 | 0.81 | GYS1 (0.49) | GYS1CYP1A2ALDH1A1HPGDMAOB | |
| SCHEMBL4396452 | 0.81 | CYP1A2 (0.52) | CYP1A2ALDH1A1HPGDPTGER1PTGER4 | |
| SCHEMBL4392684 | 0.77 | ALDH1A1 (0.49) | CYP1A2ALDH1A1HPGDMAOAMAOB | |
| SCHEMBL4402844 | 0.76 | CYP1A2 (0.51) | CYP1A2ALDH1A1HPGDPTGER1PTGER4 | |
| SCHEMBL4393141 | 0.75 | ALDH1A1 (0.54) | ALDH1A1HPGDMAPTKMT2ALMNA | |
| SCHEMBL4396155 | 0.72 | CYP1A2 (0.48) | CYP1A2MAOBCYP2D6KMT2AFFAR1 | |
| SCHEMBL4391170 | 0.71 | CYP1A2 (0.59) | CYP1A2FFAR1 | |
| SCHEMBL4391400 | 0.71 | PPARG (0.54) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6506757-B1 | A peroxisome proliferator activated receptor regulator containing a carboxylic acid derivative, is useful as a hypoglycemic agent, a hypolipidemic agent, a preventive and/or a remedy for diseases associating metabolic disorders | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-01-14 | — | — | US | disclosed |