Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16442058 | 1.00 | ALDH1A1 (0.64) | ALDH1A1HPGDGRM3GLAHSD17B10 | |
| SCHEMBL1520334 | 1.00 | ALDH1A1 (0.64) | ALDH1A1HPGDGRM3GLAHSD17B10 | |
| SCHEMBL16695294 | 0.90 | ACHE (0.60) | HPGDL3MBTL1SMN1; SMN2ACHEL3MBTL3 | |
| SCHEMBL5479680 | 0.89 | ALDH1A1 (0.62) | ALDH1A1HPGDGLAHSD17B10USP2 | |
| SCHEMBL7232221 | 0.88 | ALDH1A1 (0.61) | ALDH1A1HPGDGLAHSD17B10USP2 | |
| SCHEMBL7232214 | 0.88 | ALDH1A1 (0.61) | ALDH1A1HPGDGLAHSD17B10USP2 | |
| SCHEMBL13804124 | 0.88 | ALDH1A1 (0.61) | ALDH1A1HPGDGRM3GLAHSD17B10 | |
| SCHEMBL3319143 | 0.88 | HSD17B10 (0.74) | ALDH1A1HPGDGLAHSD17B10USP2 | |
| SCHEMBL3319140 | 0.88 | HSD17B10 (0.74) | ALDH1A1HPGDGLAHSD17B10USP2 | |
| SCHEMBL192998 | 0.86 | NPC1 (0.60) | ALDH1A1GRM3GLAHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6664271-B1 | Amide, carbamate and uredo derivatives of 3-piperidine-carboxylic acid or ester; protecting against infection by such as escherichia coli and/or actinobacillus pleuropneumoniae | ELI LILLY AND COMPANY | 2003-12-16 | — | — | US | claimed |
| US-6664271-B1 | Amide, carbamate and uredo derivatives of 3-piperidine-carboxylic acid or ester; protecting against infection by such as escherichia coli and/or actinobacillus pleuropneumoniae | ELI LILLY AND COMPANY | 2003-12-16 | — | — | US | disclosed |