Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 6/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL461128 | 0.87 | BRD4 (0.31) | PIK3CD | |
| SCHEMBL720486 | 0.87 | PIK3CA (0.41) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL715884 | 0.86 | PIK3CD (0.43) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL470114 | 0.79 | PIK3CA (0.39) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL723327 | 0.79 | — | — | |
| SCHEMBL470162 | 0.75 | PIK3CA (0.40) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL461589 | 0.72 | PIK3CA (0.45) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL470237 | 0.67 | PIK3CD (0.56) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL713193 | 0.66 | SLC9A1 (0.36) | — | |
| SCHEMBL1118851 | 0.66 | PIK3CG (0.52) | PIK3CDPIK3CBPIK3CGPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120053166-A1 | 4-Oxadiazol-2-YL-Indazoles as Inhibitors of P13 Kinases | GLAXO GROUP LIMITED (GB) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053166-A1 | 4-Oxadiazol-2-YL-Indazoles as Inhibitors of P13 Kinases | CDK3, CDK13, AKT3 | PIK3CD 11/4885PIK3CB 14/4885PIK3CG 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.