Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL723326 | 0.87 | PIK3CD (0.34) | PIK3CD | |
| SCHEMBL720486 | 0.83 | PIK3CA (0.41) | PIK3CD | |
| SCHEMBL713193 | 0.76 | SLC9A1 (0.36) | — | |
| SCHEMBL723327 | 0.76 | — | — | |
| SCHEMBL1961103 | 0.74 | HTR6 (0.36) | PIK3CD | |
| SCHEMBL470165 | 0.73 | PIP4K2A (0.36) | PIK3CD | |
| SCHEMBL717170 | 0.71 | PIP4K2A (0.35) | PIK3CD | |
| SCHEMBL1959668 | 0.68 | HTR6 (0.36) | BRD4 | |
| SCHEMBL715884 | 0.67 | PIK3CD (0.43) | PIK3CD | |
| SCHEMBL470151 | 0.66 | HTR6 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2613781-A1 | INDAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF INFLUENZA VIRUS INFECTION | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012032065-A1 | INDAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF INFLUENZA VIRUS INFECTION | GLAXO GROUP LIMITED (GB) | 2012-03-15 | — | — | WO | disclosed |