Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 10/20 | 0.46 |
| ▸ | BCHE | P06276 | 6/20 | 0.46 |
| ▸ | LTA4H | P09960 | 3/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7235053 | 0.92 | ACHE (0.45) | ACHEBCHELTA4HNAMPTHDAC1 | |
| SCHEMBL7235050 | 0.92 | ACHE (0.45) | ACHEBCHELTA4HNAMPTHDAC1 | |
| SCHEMBL7233617 | 0.91 | ACHE (0.44) | ACHEBCHELTA4HNAMPTHDAC1 | |
| SCHEMBL7233622 | 0.91 | ACHE (0.44) | ACHEBCHELTA4HNAMPTHDAC1 | |
| SCHEMBL7225272 | 0.91 | KDM4E (0.46) | ACHEBCHENAMPT | |
| SCHEMBL7225174 | 0.90 | ACHE (0.46) | ACHEBCHENAMPTHDAC1RORC | |
| SCHEMBL7225172 | 0.90 | ACHE (0.46) | ACHEBCHENAMPTHDAC1RORC | |
| SCHEMBL7227469 | 0.88 | TMEM97 (0.44) | ACHEBCHENAMPTHDAC1 | |
| SCHEMBL7233848 | 0.88 | ALDH1A1 (0.45) | ACHEBCHELTA4HNAMPTHDAC1 | |
| SCHEMBL7233846 | 0.88 | ALDH1A1 (0.45) | ACHEBCHELTA4HNAMPTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6545035-B1 | Having effect on various kinases and cycline/CDK complexes and on the proliferation of various tumour cells. | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-04-08 | — | — | US | disclosed |
| US-6319918-B1 | FOR LYMPHOMA OR SOLID TUMORS TREATMENT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-11-20 | — | — | US | disclosed |