Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6902550 | 0.79 | TRPA1 (0.56) | TRPA1TP53TDP1ALOX15HSD17B10 | |
| SCHEMBL92236 | 0.77 | MAOB (0.64) | TRPA1TP53TDP1ALDH1A1KMT2A | |
| SCHEMBL29819084 | 0.77 | MAOB (0.64) | TRPA1TP53TDP1ALDH1A1KMT2A | |
| SCHEMBL17629436 | 0.77 | MAOB (0.64) | TRPA1TP53TDP1ALDH1A1KMT2A | |
| SCHEMBL594053 | 0.77 | ACHE (0.44) | TP53TDP1HSD17B10ALDH1A1LMNA | |
| Bromide SCHEMBL31123050 | 0.76 | MAOB (0.61) | TRPA1TP53TDP1ALDH1A1KMT2A | |
| SCHEMBL27940951 | 0.76 | MAOB (0.61) | TRPA1TP53TDP1ALDH1A1KMT2A | |
| SCHEMBL17210758 | 0.76 | TRPA1 (0.52) | TRPA1TP53TDP1ALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL28958540 | 0.76 | MAOB (0.61) | TRPA1TP53TDP1ALDH1A1LMNA | |
| Ethane SCHEMBL28165560 | 0.76 | MAOB (0.61) | TRPA1TP53TDP1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541490-B1 | Treating ischemia or reoxygenation injury; preparation from a bipyridine, a benzeneboronic acid and a manganese salt | EUKARION, INC. | 2003-04-01 | — | — | US | disclosed |