Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27553396 | 0.86 | IAPP (0.46) | IAPPALDH1A1CHRNA7 | |
| SCHEMBL5270844 | 0.81 | CYP3A4 (0.39) | ALDH1A1LMNA | |
| SCHEMBL6160355 | 0.81 | IAPP (0.53) | IAPPALDH1A1CHRNA7 | |
| SCHEMBL26046404 | 0.79 | IAPP (0.46) | IAPPALDH1A1CHRNA7 | |
| SCHEMBL26046393 | 0.78 | TYR (0.63) | — | |
| SCHEMBL4374965 | 0.77 | F13A1 (0.44) | — | |
| SCHEMBL4282818 | 0.77 | TYR (0.46) | — | |
| SCHEMBL561622 | 0.77 | MAPT (0.47) | ALDH1A1LMNA | |
| SCHEMBL14747983 | 0.76 | IAPP (0.47) | IAPPALDH1A1 | |
| SCHEMBL30337626 | 0.76 | IAPP (0.47) | IAPPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608049-B2 | Indazoles | BAYER AKTIENGESELLSCHAFT (DE) | 2003-08-19 | — | — | US | disclosed |
| US-20020193610-A1 | Indazoles | BAYER AKTIENGESELLSCHAFT (DE) | 2002-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193610-A1 | Indazoles | CYP3A43, CYP3A5, CYP3A4 | IAPP 2180/4885ALDH1A1 698/4885LMNA 3230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.