Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26046348 | 0.84 | POLB (0.50) | CHRNA7 | |
| SCHEMBL6160355 | 0.81 | IAPP (0.53) | IAPPALDH1A1CHRNA7 | |
| SCHEMBL26046393 | 0.81 | TYR (0.63) | — | |
| SCHEMBL30337626 | 0.80 | IAPP (0.47) | IAPPALDH1A1 | |
| SCHEMBL14747983 | 0.80 | IAPP (0.47) | IAPPALDH1A1 | |
| SCHEMBL27553396 | 0.79 | IAPP (0.46) | IAPPALDH1A1CHRNA7 | |
| SCHEMBL1404941 | 0.79 | CHRNA7 (0.62) | IAPPCHRNA7 | |
| SCHEMBL7234435 | 0.79 | IAPP (0.46) | IAPPALDH1A1CHRNA7 | |
| SCHEMBL26046405 | 0.78 | LMNA (0.56) | ALDH1A1PKM | |
| SCHEMBL18044777 | 0.77 | TYR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746364-B2 | Enzymatic synthesis of kavalactones and flavokavains | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2023-09-05 | — | — | US | disclosed |
| US-11739354-B2 | Enzymatic synthesis of kavalactones and flavokavains | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2023-08-29 | — | — | US | disclosed |